abstract：BACKGROUND:Otitis Media (OM) is the most common disease of childhood. Twenty thousand people die each year from otitis media. It is an important cause of preventable hearing loss, affects children's intellectual performance and language development. There are very small numbers of studies done in Ethiopia concerning th...

journal_title：BMC pediatrics

authors： Tadesse B,Shimelis T,Worku M

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Intestinal parasitic infection is diversified illness and diseases caused millions morbidity among under-five children lives in developing countries particularly vulnerable rural communities. Deworming coverage in such community is low. The aim of this study was to determine the prevalence and associated ris...

journal_title：BMC pediatrics

authors： Gadisa E,Jote K

更新日期：2019-10-27 00:00:00

abstract：BACKGROUND:Children with sickle cell anemia (SCA) are highly susceptible to stroke and other manifestations of pediatric cerebral vasculopathy. Detailed evaluations in sub-Saharan Africa are limited. METHODS:We aimed to establish the frequency and types of pediatric brain injury in a cross-sectional study at a large S...

journal_title：BMC pediatrics

authors： Green NS,Munube D,Bangirana P,Buluma LR,Kebirungi B,Opoka R,Mupere E,Kasirye P,Kiguli S,Birabwa A,Kawooya MS,Lubowa SK,Sekibira R,Kayongo E,Hume H,Elkind M,Peng W,Li G,Rosano C,LaRussa P,Minja FJ,Boehme A,Idro

更新日期：2019-10-25 00:00:00

abstract：BACKGROUND:Newborn screening (NBS) for cystic fibrosis (CF) not only identifies infants with a diagnosis of CF, but also those with an uncertain diagnosis of cystic fibrosis (CF), i.e. CF transmembrane conductance regulator (CFTR)-related metabolic syndrome (CRMS) or CF screen positive inconclusive diagnosis (CFSPID). ...

journal_title：BMC pediatrics

authors： Ooi CY,Sutherland R,Castellani C,Keenan K,Boland M,Reisman J,Bjornson C,Chilvers MA,van Wylick R,Kent S,Price A,Mateos-Corral D,Hughes D,Solomon M,Zuberbuhler P,Brusky J,Durie PR,Ratjen F,Gonska T

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:Most extremely low gestational age neonates (ELGANS, postmenstrual age at birth (PMA) < 28 completed weeks) require supplemental oxygen and experience frequent intermittent hypoxemic and hyperoxemic episodes. Hypoxemic episodes and exposure to inadequately high concentrations of oxygen are associated with an...

journal_title：BMC pediatrics

authors： Maiwald CA,Niemarkt HJ,Poets CF,Urschitz MS,König J,Hummler H,Bassler D,Engel C,Franz AR,FiO2-C Study Group.

更新日期：2019-10-21 00:00:00

abstract：BACKGROUND:Hydroxyurea (HU) is recommended as standard practice for youth with sickle cell disease (SCD). Yet, despite its efficacy, HU adherence in adolescents and young adults is often poor. Poor medication adherence increases disease burden, healthcare cost and widens health disparities. Adolescence is a critical ti...

journal_title：BMC pediatrics

authors： Smaldone A,Manwani D,Aygun B,Smith-Whitley K,Jia H,Bruzzese JM,Findley S,Massei J,Green NS

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:DNA ligase IV deficiency is a rare autosomal recessive disorder caused by hypomorphic mutations in the DNA ligase IV (LIG4) gene. DNA ligase IV is an essential protein for the development of a healthy immune system as well as for the protection of genomic integrity. Apart from typical stigmata, patients with...

journal_title：BMC pediatrics

authors： Schober S,Schilbach K,Doering M,Cabanillas Stanchi KM,Holzer U,Kasteleiner P,Schittenhelm J,Schaefer JF,Mueller I,Lang P,Handgretinger R

更新日期：2019-10-11 00:00:00

abstract：BACKGROUND:Childhood undernutrition causes significant morbidity and mortality in low- and middle-income countries (LMICs). In Tanzania, the in-hospital prevalence of undernutrition in children under five years of age is approximated to be 30% with a case fatality rate of 8.8%. In Tanzania, the burden of undernourished...

journal_title：BMC pediatrics

authors： Bashaka PJ,Sawe HR,Mwafongo V,Mfinanga JA,Runyon MS,Murray BL

更新日期：2019-09-11 00:00:00

abstract：BACKGROUND:Parenting children with special health care needs can be challenging particularly if children have complex conditions. Parents may struggle to manage their child's health and their own emotions, contributing to poorer health outcomes for the family. Frequent healthcare contact presents opportunities to inter...

journal_title：BMC pediatrics

authors： Bradshaw S,Bem D,Shaw K,Taylor B,Chiswell C,Salama M,Bassett E,Kaur G,Cummins C

更新日期：2019-08-30 00:00:00

abstract：BACKGROUND:Cytomegalovirus [CMV] is a causative agent of congenital infection worldwide and often leads to neurological deficits and hearing loss in newborns. Infants born with symptomatic congenital Cytomegalovirus infection [cCMV] are at significant high risk for developing adverse long-term outcomes. In this study, ...

journal_title：BMC pediatrics

authors： Sarkar A,Das D,Ansari S,Chatterjee RP,Mishra L,Basu B,Ghosh SK,Bhattacharyay M,Chakraborty N

更新日期：2019-08-22 00:00:00

abstract：BACKGROUND:Community-acquired lower respiratory tract infections (CA-LRTIs) are the primary cause of hospitalization among children globally. A better understanding of the role of atypical pathogen infections in native conditions is essential to improve clinical management and preventive measures. The main objective of...

journal_title：BMC pediatrics

authors： Chen A,Song L,Chen Z,Luo X,Jiang Q,Yang Z,Hu L,He J,Zhou L,Yu H

更新日期：2019-08-13 00:00:00

abstract：BACKGROUND:The start of complementary feeding in infancy plays an essential role in promoting healthy eating habits. Evidence shows that it is important what infants are offered during this first introduction of solid foods: e.g. starting exclusively with vegetables is more successful for vegetable acceptance than star...

journal_title：BMC pediatrics

authors： van der Veek SMC,de Graaf C,de Vries JHM,Jager G,Vereijken CMJL,Weenen H,van Winden N,van Vliet MS,Schultink JM,de Wild VWT,Janssen S,Mesman J

更新日期：2019-08-01 00:00:00

abstract：:Following publication of the original article [1], the authors reported that name that appeared in published online version is incorrect. ...

journal_title：BMC pediatrics

authors： Yusuf A,Mamun ASMA,Kamruzzaman M,Saw A,Abo El-Fetoh NM,Lestrel PE,Hossain MG

更新日期：2019-07-26 00:00:00

abstract：BACKGROUND:Clinical and laboratory parameters can aid in the early identification of neonates at risk for bacteremia before clinical deterioration occurs. However, current prediction models have poor diagnostic capabilities. The objective of this study was to develop, evaluate and validate a screening tool for late ons...

journal_title：BMC pediatrics

authors： Walker SAN,Cormier M,Elligsen M,Choudhury J,Rolnitsky A,Findlater C,Iaboni D

更新日期：2019-07-24 00:00:00

abstract：BACKGROUND:Newborn screening (NBS) occupies a unique space at the intersection of translational science and public health. As the only truly population-based public health program in the United States, NBS offers the promise of making the successes of translational medicine available to every infant with a rare disorde...

journal_title：BMC pediatrics

authors： Bailey DB Jr,Gehtland LM,Lewis MA,Peay H,Raspa M,Shone SM,Taylor JL,Wheeler AC,Cotten M,King NMP,Powell CM,Biesecker B,Bishop CE,Boyea BL,Duparc M,Harper BA,Kemper AR,Lee SN,Moultrie R,Okoniewski KC,Paquin RS,Pe

更新日期：2019-07-17 00:00:00

abstract：BACKGROUND:Sub-Saharan Africa (SSA) alone has nine out of every 10 children living with HIV globally and monitoring in this setting remains suboptimal, even as these children grow older. With scalability of antiretroviral therapy (ART), several HIV-infected children are growing towards adolescence (over 2.1 million), w...

journal_title：BMC pediatrics

authors： Fokam J,Santoro MM,Takou D,Njom-Nlend AE,Ndombo PK,Kamgaing N,Kamta C,Essiane A,Sosso SM,Ndjolo A,Colizzi V,Perno CF

更新日期：2019-07-05 00:00:00

abstract：BACKGROUND:We have limited information on families' experiences during transition and after discharge from the neonatal intensive care unit. METHODS:Open-ended semi-structured interviews were conducted with English or Spanish- speaking families enrolled in Medicaid in an urban high-risk infant follow up clinic at a sa...

journal_title：BMC pediatrics

authors： Lakshmanan A,Kubicek K,Williams R,Robles M,Vanderbilt DL,Mirzaian CB,Friedlich PS,Kipke M

更新日期：2019-07-05 00:00:00

abstract：BACKGROUND:Seeking healthcare in children is unique since parents decide upon the type and frequency of healthcare services accessed. Mothers/caregivers lower healthcare seeking behavior is one of the major reason for increased morbidity and mortality from childhood illness in developing countries. Hence, this study ai...

journal_title：BMC pediatrics

authors： Abegaz NT,Berhe H,Gebretekle GB

更新日期：2019-07-03 00:00:00

abstract：OBJECTIVE:It has been established that genetic factors play a substantial role in the development of neonatal hyperbilirubinemia. The population of Indonesia and other Southeast Asian countries has similar, yet different genetic makeup compared to the rest of Asia. Aside from UGT1A1, variants of SLCO1B1 have also been ...

journal_title：BMC pediatrics

authors： Amandito R,Rohsiswatmo R,Halim M,Tirtatjahja V,Malik A

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:Perinatal asphyxia and resulting hypoxic-ischemic encephalopathy is a major cause of death and long-term disability in term born neonates. Up to 20,000 infants each year are affected by HIE in Europe and even more in regions with lower level of perinatal care. The only established therapy to improve outcome ...

journal_title：BMC pediatrics

authors： Maiwald CA,Annink KV,Rüdiger M,Benders MJNL,van Bel F,Allegaert K,Naulaers G,Bassler D,Klebermaß-Schrehof K,Vento M,Guimarães H,Stiris T,Cattarossi L,Metsäranta M,Vanhatalo S,Mazela J,Metsvaht T,Jacobs Y,Franz AR,AL

更新日期：2019-06-27 00:00:00

abstract：BACKGROUND:Gorham-Stout disease is a rare condition characterized by unifocal and massive type IV osteolysis (variant of idiopathic nonhereditary osteolytic disease) with a slow progression, which is self-limiting for some years. It is characterized by recurrent vascular tumors with disruption of the anatomical archite...

journal_title：BMC pediatrics

authors： Tena-Sanabria ME,Jesús-Mejenes LY,Fuentes-Herrera G,Álvarez-Martínez FA,Victorio-García NP,Núñez-Enríquez JC

更新日期：2019-06-24 00:00:00

abstract：BACKGROUND:Childhood vaccinations have been shown to be effective in protecting children against vaccine-preventable diseases. The systematic investigation of the causes of incomplete immunization is critical for the full immunization and develop health system interventions to improve immunization coverage. To date, no...

journal_title：BMC pediatrics

authors： Mekonnen AG,Bayleyegn AD,Ayele ET

更新日期：2019-06-14 00:00:00

abstract：BACKGROUND:Rotavirus antigenemia and RNAemia (the presence of rotavirus RNA in serum) have been commonly identified among paediatric patients with acute gastroenteritis. In this study we examined the association between rotavirus antigenemia and clinical features, and sought to determine the genotypes of rotaviruses de...

journal_title：BMC pediatrics

authors： Justino MCA,Campos EA,Mascarenhas JDP,Soares LS,Guerra SFS,Furlaneto IP,Pavão MJC Jr,Maciel TS,Farias FP,Bezerra OM,Vinente CBG,Barros RJS,Linhares AC

更新日期：2019-06-12 00:00:00

abstract：BACKGROUND:Invasive S. pyogenes diseases are uncommon, serious infections with high case fatality rates (CFR). There are few publications on this subject in the field of pediatrics. This study aimed at characterizing clinical and laboratory aspects of this disease in Chinese children. PATIENTS AND METHODS:A retrospect...

journal_title：BMC pediatrics

authors： Hua CZ,Yu H,Xu HM,Yang LH,Lin AW,Lyu Q,Lu HP,Xu ZW,Gao W,Chen XJ,Wang CQ,Jing CM

更新日期：2019-06-05 00:00:00

abstract：BACKGROUND:Insufficient elastin synthesis leads to vascular complications and arterial hypertension in children with Williams-Beuren syndrome. Restoring sufficient quantity of elastin should then result in prevention or inhibition of vascular malformations and improvement in arterial blood pressure. METHODS:The aim of...

journal_title：BMC pediatrics

authors： Kassai B,Bouyé P,Gilbert-Dussardier B,Godart F,Thambo JB,Rossi M,Cochat P,Chirossel P,Luong S,Serusclat A,Canterino I,Mercier C,Rabilloud M,Pivot C,Pirot F,Ginhoux T,Coopman S,Grenet G,Gueyffier F,Di-Fillippo S,Be

更新日期：2019-05-28 00:00:00

abstract：BACKGROUND:Socioeconomic status is an important factor affecting the initiation and cessation of breastfeeding. However, limited evidence exists regarding the association between socioeconomic status and breastfeeding behavior in China on a national level. This study aims to investigate the relationship between socioec...

journal_title：BMC pediatrics

authors： Chen C,Cheng G,Pan J

更新日期：2019-05-27 00:00:00

abstract：BACKGROUND:Schoolbags and the consequences of carrying them, particularly those associated with overload, are often studied as a health concern. Modifications in gait and posture were reported when children carried loads that corresponded to more than 10% of their body weight (BW). The aims of this study were to verify...

journal_title：BMC pediatrics

authors： Barbosa J,Marques MC,Izquierdo M,Neiva HP,Barbosa TM,Ramírez-Vélez R,Alonso-Martínez AM,García-Hermoso A,Aguado-Jimenez R,Marinho DA

更新日期：2019-05-17 00:00:00

abstract：BACKGROUND:Although various studies have shown the effect of vigorous physical activity on academic achievements, no studies have investigated the effect of vitamin E levels on academic performance. The present study aimed to assess the association between physical activity, vitamin E levels and total antioxidant capac...

journal_title：BMC pediatrics

authors： Alghadir AH,Gabr SA,Iqbal ZA,Al-Eisa E

更新日期：2019-05-17 00:00:00

abstract：BACKGROUND:Pediatricians are advised by the Austrian ministry of health to be vaccinated against diphtheria, tetanus, pertussis, poliomyelitis, measles, mumps, rubella, varicella, hepatitis A, hepatitis B, meningococcus ACWY and meningococcus B, pneumococcus and seasonal influenza. As they take care of a vulnerable pat...

journal_title：BMC pediatrics

authors： Diesner SC,Peutlberger S,Voitl P

更新日期：2019-05-16 00:00:00

abstract：BACKGROUND:Autosomal dominant tubulointerstitial kidney disease (ADTKD) caused by UMOD gene mutation (ADTKD-UMOD) is rare in children, characterized by hyperuricemia, gout, and progressive chronic kidney disease. It usually leads to end-stage renal failure at fiftieth decades. Here, we report a 3-year-old Chinese boy i...

journal_title：BMC pediatrics

authors： Yang J,Zhang Y,Zhou J

更新日期：2019-05-08 00:00:00

abstract：OBJECTIVE:To evaluate the association between hematological parameters at birth and the risk of moderate-severe bronchopulmonary dysplasia (BPD) in a cohort of extremely preterm infants. METHODS:This is a retrospective study of all extremely premature infants admitted to the neonatal intensive care unit, Shenzhen Mate...

journal_title：BMC pediatrics

authors： Chen X,Li H,Qiu X,Yang C,Walther FJ

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND:Total colonic and small bowel aganglionosis (TCSA) occurs in less than 1% of all Hirschsprung's disease patients. Currently, the mainstay of treatment is surgery. However, in patients with TCSA, functional outcomes are often poor. A characteristic transition zone in TCSA can be difficult to identify which ma...

journal_title：BMC pediatrics

authors： Salimi Jazi F,Chandler JM,Thorson CM,Sinclair TJ,Hazard FK,Kerner JA,Dutta S,Dunn JCY,Chao SD

更新日期：2019-04-05 00:00:00

abstract：BACKGROUND:Comprehensive data are needed to evaluate the burden of low birthweight. Analysis of routine data on health-care utilization during early childhood were used to test the hypothesis that infants with low birthweight have (i) increased inpatient health-care utilization, (ii) higher hospital costs and (iii) dif...

journal_title：BMC pediatrics

authors： Rüdiger M,Heinrich L,Arnold K,Druschke D,Reichert J,Schmitt J

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Mutations in the PIGV, PIGO, PIGL, PIGY, PGAP2, PGAP3, and PIGW genes have recently been reported to cause hyperphosphatasia accompanied by mental retardation syndrome (HPMRS); the latter is an autosomal-recessive neurological disorder typically characterised by recurrent seizures, intellectual disability, a...

journal_title：BMC pediatrics

authors： Fu L,Liu Y,Chen Y,Yuan Y,Wei W

更新日期：2019-02-27 00:00:00

abstract：BACKGROUND:Primary lymphomas of the gastrointestinal tract are rare, accounting for only 1 to 4% of malignancies arising in the stomach, small intestine, or colon. The stomach is the most common extranodal site of lymphoma and gastric mucosa-associated lymphoid tissue (MALT) lymphoma accounts for 40% of primary gastric...

journal_title：BMC pediatrics

authors： Chang YT,Huang MY,Shih HH,Wu CC,Lu TY,Lin PC

更新日期：2019-02-19 00:00:00

abstract：BACKGROUND:Donor human milk (DHM) is the best alternative for preterm infants when their own mother's milk is unavailable. DHM should be pasteurized to guarantee microbiological safety; however, this process can influence the macronutrient content. The aim of this study was to investigate the effect of Holder pasteuriz...

journal_title：BMC pediatrics

authors： Piemontese P,Mallardi D,Liotto N,Tabasso C,Menis C,Perrone M,Roggero P,Mosca F

更新日期：2019-02-12 00:00:00

abstract：BACKGROUND:Newborn resuscitation is a life-saving intervention for birth asphyxia, a leading cause of neonatal mortality. Improving provider newborn resuscitation skills is critical for delivering quality care, but the retention of these skills has been a challenge. Tanzania implemented a national newborn resuscitation...

journal_title：BMC pediatrics

authors： Drake M,Bishanga DR,Temu A,Njozi M,Thomas E,Mponzi V,Arlington L,Msemo G,Azayo M,Kairuki A,Meda AR,Isangula KG,Nelson BD

更新日期：2019-02-07 00:00:00

abstract：BACKGROUND:In Senegal in 2015, an estimated 4800 children were living with HIV, with 1200 receiving ARV treatment, of whom half had follow-up care in decentralized sites outside Dakar. However, until now no studies have determined the efficacy of pediatric treatment in decentralized settings, even though the emergence ...

journal_title：BMC pediatrics

authors： Cissé AM,Laborde-Balen G,Kébé-Fall K,Dramé A,Diop H,Diop K,FatouNiasse-Traoré,Coulibaly M,Have NN,Vidal N,Thiam S,Wade AS,Peeters M,Taverne B,Msellati P,Touré-Kane C

更新日期：2019-02-05 00:00:00

abstract：BACKGROUND:Pneumomediastinum is an uncommon cause of neonatal respiratory distress. Clinical history and examination of the neonate may be uninformative in determining the aetiology of the respiratory distress. Chest x-ray can be diagnostic of pneumomediastinum however is often difficult to interpret. CASE PRESENTATIO...

journal_title：BMC pediatrics

authors： Teo SSS,Priyadarshi A,Browning Carmo K

更新日期：2019-01-31 00:00:00

abstract：BACKGROUND:Urinary tract infection (UTI) is one of most common pediatric infections. The study was designed to assess the clinical profile, common bacterial microorganisms causing UTI and their antimicrobial susceptibility patterns at B. P. Koirala Institute of Health Sciences (BPKIHS) hospital. METHODS:This is a pros...

journal_title：BMC pediatrics

authors： Shrestha LB,Baral R,Poudel P,Khanal B

更新日期：2019-01-29 00:00:00